中國醫藥大學附設醫院細胞治療中心 江智聖 博士 新創技術： 開發靶向性硫酸多醣酯之磁性奈米技術平台：結合診斷、治療、追蹤之三合一精準療法▶more 研究專長： 智慧藥物傳遞系統、生醫材料、標靶治療、精準醫療、轉譯醫學

現職

中國醫藥大學附設醫院助理研究員

學歷

國立交通大學材料科學與工程學系博士

經歷

2016美國東北大學化工系訪問學者
2020科技部未來科技獎
國立陽明大學醫工系博士後研究員
構思創精準治療股份有限公司籌備處技術長

重要發明與專利

1. Chiang C-S, Lin Y-J, Lee R, Lai Y-H, Cheng H-W, Hsieh C-H, et al. Combination of fucoidan-based magnetic nanoparticles and immunomodulators enhances tumour-localized immunotherapy. Nature Nanotechnology. 2018; 13, 746–54.
2. Chiang C-S, Shih I-J, Shueng P-W, Kao M, Chang L-W, Chen S-F, Chen M-H and Liu T-Y, Tumor cell-targeting radiotherapy in the treatment of glioblastoma multiforme using linear accelerators. Acta Biomaterialia. 2021; 125, 300-311.
3. Chiang C-S, Shen Y-S, Liu J-J, Shyu W-C, Chen S-Y. Synergistic Combination of Multistage Magnetic Guidance and Optimized Ligand Density in Targeting a Nanoplatform for Enhanced Cancer Therapy. Advanced Healthcare Materials. 2016;5(16):2131-41.
4. Cheng H-W, Tsao H‐Y, Chiang C-S*, Chen S-Y, Advances in Magnetic Nanoparticle‐Mediated Cancer Immune‐Theranostics. Advanced Healthcare Materials. 2021; 10(1), 2001451.
5. Li W-M, Chiang C-S, Huang W-C, Su C-W, Chiang M-Y, Chen J-Y, et al. Amifostine-conjugated pH-sensitive calcium phosphate-covered magnetic-amphiphilic gelatin nanoparticles for controlled intracellular dual drug release for dual-targeting in HER-2-overexpressing breast cancer. Journal of Controlled Release. 2015;220:107-18. (Equal contribution to first author)
6. Chiang C-S, Tseng Y-H, Liao B-J, Chen S-Y. Magnetically Targeted Nanocapsules for PAA-Cisplatin-Conjugated Cores in PVA/SPIO Shells via Surfactant-Free Emulsion for Reduced Nephrotoxicity and Enhanced Lung Cancer Therapy. Advanced Healthcare Materials. 2015;4(7):1066-75.
7. Chiang C-S, Hu S-H, Liao B-J, Chang Y-C, Chen S-Y. Enhancement of cancer therapy efficacy by trastuzumab-conjugated and pH-sensitive nanocapsules with the simultaneous encapsulation of hydrophilic and hydrophobic compounds. Nanomedicine: Nanotechnology, Biology and Medicine. 2014;10(1):99-107.
8. Chiang C-S, Kao Y-C, Webster T. J., Shyu W-C, Cheng H-W, Liu T-Y, and Chen S-Y, Circulating Tumour Cells-Targeting Au-Nanocages-Mediated Bimodal Phototherapeutic Properties Enriched by Magnetic Nanocore. Journal of materials chemistry B. 2020; 8(25), 5460–5471.
9. Chiang C-S, Hu S-H, and Chen S-Y, Antibody-conjugated double-emulsion nanocapsule and preparation methods thereof 2017, US Patent 9603798B2/ CN104208717B/ KR101767906B1/ JP6335281B2/ CA2910076C/ AU2014274028B2/ TWI482782B (Granted)
10. Shyu W-C, Chen S-Y, Chiang C-S, Hsieh C-H, Lin Y-J, Tsai C-H, Immunomagnetic nanocapsule, pharmaceutical composition thereof for treating cancer and kit for treating cancer, US10736964/ JP6771509/ TW I664983/ AU2018262962 (Granted)